Anti- PARP1 Antibody | FNab09939

Anti- PARP1 Antibody | FNab09939 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: protein A+G purified

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 4A9

Isotype: IgG1

Storage: 0.01MPBS pH 7.4, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: PARP1 (poly (ADP-ribose) polymerase 1) is a nuclear enzyme catalyzing the poly (ADP-ribosyl) ation of many key proteins in vivo. The normal function of PARP1 is the routine repair of DNA damage. Activated by DNA strand breaks, the PARP1 is cleaved into an 85 to 89-kDa COOH-terminal fragment and a 24-kDa NH2-terminal peptide by caspases during the apoptotic process. The appearance of PARP fragments is commonly considered as an important biomarker of apoptosis.

Immunogen: poly (ADP-ribose) polymerase 1

synonyms: ADPRT, ADPRT 1, ADPRT1, pADPRT 1, PARP, PARP 1, PARP1, poly (ADP ribose) polymerase 1, Poly [ADP ribose] polymerase 1, Poly[ADP ribose] synthase 1, PPOL

Molecular weight (observed) : 115 kDa, 89 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, IHC, WB, IF

Recomended Dillution : WB: 1:5000 - 1:30000; IHC: 1:100 - 1:1000; IF: 1:50 - 1:500

Research Area: Metabolism