Anti-PFKFB2 Antibody | A1997

The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.

A1997 | Anti-PFKFB2 Antibody DataSheet

Antibody Target: PFKFB2

Target Alternative Name: 6-phosphofructo-2-kinase/fructose-2;6-bisphosphatase 2; 6PF-2-K/Fru-2;6-P2ase 2; PFK/FBPase 2; 6PF-2-K/Fru-2;6-P2ase heart-type isozyme

Tag Line: Affinity purified rabbit polyclonal antibody to detect PFKFB2 expression in human and monkey samples

Category: Primary antibody

Host: Rabbit

Isotype: IgG

Species Reactivities: Monkey, Human

Immunogen Sequence: KLH-conjugated synthetic peptide targeting a sequence within the N-term region of human PFKFB2

Accession #: O60825

Gene ID: 5208

Appearance: Colorless liquid

Form: Liquid

Concentration:

Formulation: In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide

Purification: Affinity purified

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting

Positive Control:

Application And Usages: WB 1:500 - 1:1000, IHC 1:100 - 1:200, IF 1:100 - 1:500

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: True

Immunocytochemistry Verified: True

Immunofluorescence Verified: True

Immunoprecipitation Verified: False

FACS Verified: False

ELISA Verified: False

ChIP Verified: False

Dot Blot Verified: False

Flow Cytometry Verified: False