Anti-Phospho-BRCA1 (S1423) Polyclonal Antibody | A2360

Anti-Phospho-BRCA1 (S1423) Polyclonal Antibody | A2360

Description: The BRCA1 protein is an E3 ubiquitin ligase that plays a central role in DNA repair and has tumor suppressor functions. Among other functions, BRCA1 coordinates DNA repair, cell cycle arrests triggered by ionizing radiation, and transcriptional regulation of other genes involved in DNA repair and maintenance. Mutations in BRCA1 are observed in approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers.

Antibody Target: Human BRCA1 phosphorylated at serine 1423

Target Alternative Name: BRCA1; BRCAI; BRCC1; BROVCA1; FANCS; IRIS; PNCA4; PPP1R53; PSCP; RNF53

Tag Line: Critical tumor suppressor that maintains genomic stability

Category: GM-CSF

Lot #:

Host: Rabbit

Antibody Type: Polyclonal

Isotype: Rabbit IgG

Clone#:

Species Reactivities: Rat, Human

Immunogen Sequence: A synthetic phosphorylated peptide around serine 1423 of human BRCA1

Accession #: P38398

Gene Id: 672

Form: Liquid

Appearance: Rabbit polyclonal

Concentration:

Formulation: In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3

Purification: Affinity purification

Application: Immunofluorescence (IF) Immunohistochemistry (IHC) Western Blotting

Positive Control: Immunofluorescence (IF) Immunohistochemistry (IHC) Western Blotting

Application And Usages:

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: FALSE

Immunocytochemistry Verified: TRUE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: TRUE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: TRUE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE