Anti-PKLR monoclonal Antibody | MB62359

Anti-PKLR monoclonal Antibody | MB62359 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: FC, WB

Application Range: WB 1:2000, FLOW 1:100

Background: The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA) . Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: pyruvate kinase, liver and RBC

Molecular Weight: 61.6 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: PK1; PKL; PKR; PKRL; RPK

Immunogen: Full length human recombinant protein of human PKLR (NP_000289) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A