Anti-PON1 Antibody (Clone# ARC2001) | A2229

This gene encodes a member of the paraoxonase family of enzymes and exhibits lactonase and ester hydrolase activity. Following synthesis in the kidney and liver, the enzyme is secreted into the circulation, where it binds to high-density lipoprotein (HDL) particles and hydrolyzes thiolactones and xenobiotics, including paraoxon, a metabolite of the insecticide parathion. Polymorphisms in this gene may be associated with coronary artery disease and diabetic retinopathy. The gene is found in a cluster of three related paraoxonase genes on chromosome 7.

A2229 | Anti-PON1 Antibody (Clone# ARC2001) DataSheet

Antibody Target: PON1

Target Alternative Name: Paraoxonase 1, PON 1, K-45, ESA, PON, EC 3.1.1.81, EC 3.1.1.2, EC 3.1.8.1, MVCD5, PON1

Tag Line: Affinity purified rabbit monoclonal antibody to detect the expression of PON1 in human, mouse and rat samples

Category: Primary antibody

Host: Rabbit

Isotype: IgG

Species Reactivities: Rat,Mouse,Human

Immunogen Sequence: Synthetic peptide derived from human PON1

Accession #: P27169

Gene ID: 5444

Appearance: Colorless liquid

Form: Liquid

Concentration:

Formulation: In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3

Purification: Affinity purified

Application: Immunohistochemistry (IHC),Immunofluorescence (IF),Western Blotting

Positive Control:

Application And Usages: WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: TRUE

Immunocytochemistry Verified: FALSE

Immunofluorescence Verified: TRUE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE