Anti- PTPRS Antibody | FNab06948

Anti- PTPRS Antibody | FNab06948 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Type II a receptor protein tyrosine phosphatases (rPTPσ) are cell surface receptors important for nervous system development, function, and repair.The expression of rPTPσ has previously been reported in b-cells and other target organs for INS although the probes chosen did not permit to distinguish between the splice variants.Proteolytic processing near the transmembrane domain generates an extracellular N-terminal E-domain of 130 kDa and a C-terminal P-domain of approximately 85 kDa of rPTPσ, and the short splice variants rPTPσ 3 and 4 contain an E-domain of 95 kDa (PMID: 16552719) . rPTPσ expression was observed in tissue lysates of the adult mouse sensory-motor cortex and thoracic spinal cord (T8-T10) as a 75-80kDa immunoreactive band (PMID: 19780196) .

Immunogen: protein tyrosine phosphatase, receptor type, S

synonyms: N/A

Molecular weight (observed) : 75-100 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB

Recomended Dillution : WB: 1:200-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

Research Area: Signal Transduction, Metabolism, Immunology, Developmental biology, Neuroscience