Anti-RALBP1 (RIP1) monoclonal Antibody | MB62390

Anti-RALBP1 (RIP1) monoclonal Antibody | MB62390 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: IF, IHC, IP, WB

Application Range: WB 1:2000, IHC 1:50, IF 1:100, IP: 4ug/mL

Background: Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S- (2,4-dinitrophenyl) -glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDC2 to switch off endocytosis, One of its substrates would be EPN1/Epsin

Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: ralA binding protein 1

Molecular Weight: 76.0 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: RIP1; RLIP1; RLIP76

Immunogen: Full length human recombinant protein of human RALBP1 (NP_006779) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A