710
Anti- RGS7 Antibody | FNab07273
- SKU:
- 710-FNab07273-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- RGS7 Antibody | FNab07273 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:10521509, PubMed:10862767) . The RGS7/GNB5 dimer enhances GNAO1 GTPase activity (PubMed:10521509) . May play a role in synaptic vesicle exocytosis (PubMed:12659861) . Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling (PubMed:15897264) .
Immunogen: regulator of G-protein signaling 7
synonyms: N/A
Molecular weight (observed) : 62 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recomended Dillution : WB: 1:500-1:2000; IHC: 1:20-1:200
Research Area: Signal Transduction