710
Anti- RPE65 Antibody | FNab07401
- SKU:
- 710-FNab07401-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- RPE65 Antibody | FNab07401 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. The enzymatic activity is linearly dependent of the expression levels and membrane association.
Immunogen: retinal pigment epithelium-specific protein 65kDa
synonyms: LCA2, mRPE65, rd12, Retinoid isomerohydrolase, Retinol isomerase, RP20, RPE65, sRPE65
Molecular weight (observed) : 65kd, 61kd
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IF
Recomended Dillution : WB: 1:500-1:5000
Research Area: Neuroscience, Metabolism