Anti-SEC61B (KO Validated) Antibody | A2126

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the beta-subunit protein. The Sec61 subunits are also observed in the post-ER compartment, suggesting that these proteins can escape the ER and recycle back. There is evidence for multiple poly-adenylated sites for this transcript.

A2126 | Anti-SEC61B (KO Validated) Antibody DataSheet

Antibody Target: SEC61B

Target Alternative Name: SEC61B

Tag Line: Affinity purified rabbit polyclonal antibody to detect expression of Sec61 complex beta subunit in human, mouse and rat samples

Category: Primary antibody

Host: Rabbit

Isotype: IgG

Species Reactivities: Rat,Mouse,Human

Immunogen Sequence: Synthetic peptide targeting a sequence around aa 1-96 of human SEC61B

Accession #: P60468

Gene ID: 10952

Appearance: Colorless liquid

Form: Liquid

Concentration:

Formulation: In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3

Purification: Affinity purified

Application: Immunofluorescence (IF),Western Blotting

Positive Control:

Application And Usages: WB 1:500 - 1:2000, IF 1:50 - 1:200

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: TRUE

Immunocytochemistry Verified: FALSE

Immunofluorescence Verified: TRUE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE