Anti- SPPL2A Antibody | FNab08191

Anti- SPPL2A Antibody | FNab08191 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: SPPL2A (Signal peptide peptidase-like 2A) is also named as IMP3 (Intramembrane protease 3), PSL2 (Presenilin-like protein 2) and belongs to the peptidase A22B family. It is an aspartyl intramembrane protease, has been implicated in the proteolysis of TNF-alpha, Fas Ligand and Bri2 and endogenous signal-peptide-peptidase-like2A (SPPL2a) is localised in lysosomes/late endosomes (PMID:21896273) .

Immunogen: signal peptide peptidase-like 2A

synonyms: N/A

Molecular weight (observed) : 58 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recomended Dillution : WB: 1:200-1:2000; IHC: 1:20-1:200

Research Area: Signal Transduction, Metabolism