Anti- STIM1 Antibody | FNab08321

Anti- STIM1 Antibody | FNab08321 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 4G6

Isotype: IgG2a

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Plays a role in mediating store-operated Ca (2+) entry (SOCE), a Ca (2+) influx following depletion of intracellular Ca (2+) stores (By similarity) . Acts as Ca (2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca (2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca (2+) release-activated Ca (2+) (CRAC) channel subunit ORAI1 (PubMed:16208375) . Involved in enamel formation (By similarity) . Activated following interaction with TMEM110/STIMATE, leading to promote STIM1 conformational switch (By similarity) .

Immunogen: stromal interaction molecule 1

synonyms: D11S4896E, GOK, STIM1, stromal interaction molecule 1

Molecular weight (observed) : 77kd

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IP, IHC, IF, FC

Recomended Dillution : WB: 1:200-1:2000 IHC: 1:50-1:500

Research Area: Neuroscience, Immunology