Anti- SYTL2 Antibody | FNab08460

Anti- SYTL2 Antibody | FNab08460 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Isoform 1 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for cytotoxic granule docking at the immunologic synapse. Isoform 4 binds phosphatidylserine (PS) and phosphatidylinositol-4, 5-bisphosphate (PIP2) and promotes the recruitment of glucagon-containing granules to the cell membrane in pancreatic alpha cells. Binding to PS is inhibited by Ca (2+) while binding to PIP2 is Ca (2+) insensitive.

Immunogen: synaptotagmin-like 2

synonyms: KIAA1597, SGA72M, SLP2, SLP2A

Molecular weight (observed) : 100-105 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF, IP, FC

Recomended Dillution : WB: 1:500-1:2000; IHC: 1:20-1:200

Research Area: Cell Division and Proliferation