Anti- TLE1 Antibody | FNab08720

Anti- TLE1 Antibody | FNab08720 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 8F4

Isotype: IgG1

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.

Immunogen: transducin-like enhancer of split 1 (E (sp1) homolog, Drosophila)

synonyms: E (Sp1) homolog, ESG, ESG1, GRG1, TLE1

Molecular weight (observed) : 85 kDa

Reactivity Species: Human

Tested Application: ELISA, WB, IF, IHC, IP

Recomended Dillution : WB: 1:500-1:2000; IHC: 1:20-1:200

Research Area: Signal Transduction, Metabolism, Cancer, Immunology, Developmental biology