Anti-TNF-? (Humicade) Biotinylated Antibody | A2182

Recombinant monoclonal antibody to TNF-?. Manufactured using recombinant technology with variable regions (i.e. specificity) from the hybridoma CDP 571 (Humicade). The antibody binds specifically to TNF-?, a pro-inflammatory cytokine that stimulates the release of other cytokines e.g. IL-1, IL-6, and GM-CSF as well as secretion of ICAM-1 and VCAM-1 from endothelial cells. It stimulates acute phase responses and acts as a chemoattractant for NK cells and monocytes/macrophages. The antibody reached Phase II clinical trials with Celltech, UCB

A2182 | Anti-TNF-? (Humicade) Biotinylated Antibody DataSheet

Antibody Target: TNF-?

Target Alternative Name: BAY 103356, BAY W 3356, CDP 571, DIF, TNFA, TNFSF2, TNLG1F, TNF-alpha, APC1 Protein

Tag Line: Recombinant monoclonal antibody to detect the biotinylated TNF-? in human samples

Category: Primary antibody

Host: Recombinant

Isotype: IgG4, kappa

Species Reactivities: Human

Immunogen Sequence: Human TNF-?

Accession #: P01375

Gene ID: 7124

Appearance: Colorless liquid

Form: Liquid

Concentration:

Formulation: In PBS, pH 7.2, 30% glycerol, 0.5% BSA, 0.5 mM EDTA and 0.03% proclin

Purification: Affinity purified using protein A

Application: ELISA

Positive Control:

Application And Usages: ELISA 0.1 µg - 1 µg/ml

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: FALSE

Immunocytochemistry Verified: FALSE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: TRUE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE