710
Anti- TNFAIP1 Antibody | FNab08817
- SKU:
- 710-FNab08817-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- TNFAIP1 Antibody | FNab08817 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Protein A+G purification
Purity: ≥95% as determined by SDS-PAGE
Host: Mouse
Clonality: monoclonal
Clone ID: 2H3
Isotype: IgG1
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR (BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.
Immunogen: tumor necrosis factor, alpha-induced protein 1 (endothelial)
synonyms: BACURD2, EDP1
Molecular weight (observed) : 36 kDa
Reactivity Species: Human
Tested Application: ELISA, IHC, WB, IF
Recomended Dillution : WB: 1:1000-1:6000; IHC: 1:50-1:600
Research Area: Metabolism