710
Anti- TRAF4 Antibody | FNab08919
- SKU:
- 710-FNab08919-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- TRAF4 Antibody | FNab08919 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD (P) H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.
Immunogen: TNF receptor-associated factor 4
synonyms: CART1, MLN62, RNF83
Molecular weight (observed) : 54 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, IP, WB, IF, IHC
Recomended Dillution : WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Research Area: Stem Cells, Signal Transduction, Developmental biology