Anti- transcription termination factor-Specific Antibody | FNab08928

Anti- transcription termination factor-Specific Antibody | FNab08928 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Protein A+G purification

Purity: ≥95% as determined by SDS-PAGE

Host: Mouse

Clonality: monoclonal

Clone ID: 7C4

Isotype: IgG1

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: TTF1 is a multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. It plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5, TTF1 recovers DNA-binding activity. The antibody is specific to TTF1.

Immunogen: transcription termination factor, RNA polymerase I

synonyms: RNA polymerase I termination factor, Transcription termination factor I, TFF1, TFF-I

Molecular weight (observed) : 43 kDa, 66 kDa

Reactivity Species: Human, Mouse

Tested Application: ELISA, WB

Recomended Dillution : WB: 1:1000-1:10000

Research Area: Cancer, Metabolism