Anti- TRIP13 Antibody | FNab08997

Anti- TRIP13 Antibody | FNab08997 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (By similarity) .

Immunogen: thyroid hormone receptor interactor 13

synonyms: 16E1 BP, 16E1BP, PCH2, TR interacting protein 13, TRIP 13, TRIP13

Molecular weight (observed) : 49 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IF

Recomended Dillution : WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:50-1:500

Research Area: Signal Transduction