Anti- TRIP4 Antibody | FNab08998

Anti- TRIP4 Antibody | FNab08998 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription. May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a role in thyroid hormone receptor and estrogen receptor transactivation (PubMed:10454579, PubMed:25219498) . Also involved in androgen receptor transactivation (By similarity) . Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B (PubMed:12077347) . May play a role in the development of neuromuscular junction (PubMed:26924529) .

Immunogen: thyroid hormone receptor interactor 4

synonyms: TRIP4, TRIP 4, TR interacting protein 4, ASC 1, HsT17391

Molecular weight (observed) : 66 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IP, IHC

Recomended Dillution : WB: 1:500-1:5000

Research Area: Metabolism