Anti- TRMT5 Antibody | FNab09007

Anti- TRMT5 Antibody | FNab09007 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Involved in mitochondrial tRNA methylation (PubMed:26189817) . Specifically methylates the N1 position of guanosine-37 in various tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

Immunogen: TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)

synonyms: TRMT5, tRNA methyltransferase 5, TRM5, tRNA [GM37] methyltransferase, M1G methyltransferase

Molecular weight (observed) : 58 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recomended Dillution : WB: 1:500-1:5000

Research Area: Metabolism