Anti-USP2 Antibody | A2146

This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease that is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX, and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

A2146 | Anti-USP2 Antibody DataSheet

Antibody Target: USP2

Target Alternative Name: 41 kDa ubiquitin specific protease, 41 kDa ubiquitin-specific protease, Deubiquitinating enzyme 2, Ubiquitin carboxyl terminal hydrolase 2, Ubiquitin carboxyl-terminal hydrolase 2, ubiquitin specific peptidase 2, Ubiquitin specific processing protease 2, Ubiquitin specific protease 12, Ubiquitin specific protease 9, Ubiquitin thioesterase 2, Ubiquitin-specific-processing protease, UBP-t, UBP2, UBP41, USP2, USP9

Tag Line: Rabbit polyclonal antibody to detect the expression of USP2 in human and mouse samples

Category: Primary antibody

Host: Rabbit

Isotype: IgG

Species Reactivities: Mouse,Human

Immunogen Sequence: Recombinant Human Ubiquitin carboxyl-terminal hydrolase 2 protein

Accession #: O75604

Gene ID: 9099

Appearance: Colorless liquid

Form: Liquid

Concentration:

Formulation: In 0.01 M PBS, pH 7.4, 50% Glycerol, 0.03% proclin 300

Purification: Protein G purified

Application: Immunofluorescence (IF),Western Blotting

Positive Control:

Application And Usages: WB 1:1000-1:5000, IF 1:50-1:200

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: TRUE

Immunocytochemistry Verified: FALSE

Immunofluorescence Verified: TRUE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE