Anti- USP21 Antibody | FNab09318

Anti- USP21 Antibody | FNab09318 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Deubiquitinates histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A releaves the repression of di-and trimethylation of histone H3 at 'Lys-4', resulting in regulation of transcriptional initiation. Regulates gene expression via histone H2A deubiquitination (By similarity) . Also capable of removing NEDD8 from NEDD8 conjugates but has no effect on Sentrin-1 conjugates (PubMed:10799498) . Deubiquitinates BAZ2A/TIP5 leading to its stabilization (PubMed:26100909) .

Immunogen: ubiquitin specific peptidase 21

synonyms: Deubiquitinating enzyme 21, Ubiquitin thiolesterase 21, USP16, USP21, USP23

Molecular weight (observed) : 63 kDa

Reactivity Species: Human

Tested Application: ELISA, WB, IHC, IP

Recomended Dillution : WB: 1:200-1:2000; IHC: 1:20-1:200

Research Area: Epigenetics, Metabolism