710
Anti- USP34 Antibody | FNab09327
- SKU:
- 710-FNab09327-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- USP34 Antibody | FNab09327 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1) -mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Immunogen: ubiquitin specific peptidase 34
synonyms: Deubiquitinating enzyme 34, FLJ43910, KIAA0570, KIAA0729, Ubiquitin thiolesterase 34, USP34
Molecular weight (observed) : 47 kDa
Reactivity Species: Human, Mouse
Tested Application: ELISA, WB, IHC
Recomended Dillution : WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:20-1:200
Research Area: Epigenetics, Metabolism