Anti-USP5 monoclonal Antibody | MB62447

Anti-USP5 monoclonal Antibody | MB62447 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: IF, IHC, WB

Application Range: WB: 1:200 - 1:1000, IHC 1:50, IF 1:100

Background: Ubiquitin (see MIM 191339) -dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]) . [supplied by OMIM]

Storage & Stability: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: ubiquitin specific peptidase 5

Molecular Weight: 93.1 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: ISOT

Immunogen: Full length human recombinant protein of human USP5 (NP_003472) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A