Anti- VAPA Antibody | FNab09369

Anti- VAPA Antibody | FNab09369 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites (PubMed:25447204) . The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface (PubMed:25447204) . With OSBPL3, may regulate ER morphology (PubMed:16143324) . May play a role in vesicle trafficking (PubMed:11511104, PubMed:19289470) .

Immunogen: VAMP (vesicle-associated membrane protein) -associated protein A, 33kDa

synonyms: 33 kDa VAMP associated protein, hVAP 33, VAMP A, VAMP associated protein A, VAP 33, VAP A, VAP33, VAPA

Molecular weight (observed) : 33 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB

Recomended Dillution : WB: 1:500-1:5000; IHC: 1:50-1:200；IF: 1:10-1:100; IP: 1:500-1:5000

Research Area: Signal Transduction