Anti- VMAT2 Antibody | FNab09418

Anti- VMAT2 Antibody | FNab09418 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: VMAT2 is a vesicular monoamine transporter that is responsible for the uptake and storage of monoamines (dopaine, norepinephrine, epinephrine, histamine and serotonin) in neurons, endocrine cells, and tumors deriving from these cells. Histamine-producing endocrine tumors (gastric carcinoids) expressed VMAT2 almost exclusively, thus VMAT2 is useful in classification of neuroendocrine tumors. Reduced expression of VMAT2 has often been observed in Parkinson’s diseased (PD) brain, and detection of VMAT2 can be used to reflect the dopamine neuron loss and predict the disease process. VMAT2 migrated as a major band of 65-75 kDa and a minor band of 55-60 kDa, representing the glycosylated form and native form.

Immunogen: solute carrier family 18 (vesicular monoamine), member 2

synonyms: Monoamine transporter, SLC18A2, SVAT, SVMT, VAT2, Vesicular amine transporter 2, VMAT2

Molecular weight (observed) : 56 kDa, 66 kDa

Reactivity Species: Human

Tested Application: ELISA, WB, IHC, IP

Recomended Dillution : WB: 1:200-1:2000

Research Area: Neuroscience