Anti- VPS37A Antibody | FNab09440

Anti- VPS37A Antibody | FNab09440 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.

Immunogen: vacuolar protein sorting 37 homolog A (S. cerevisiae)

synonyms: ESCRT I complex subunit VPS37A, FLJ32642, FLJ42616, HCRP1, hVps37A, PQBP2, VPS37A

Molecular weight (observed) : 44 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB, IF, IP

Recomended Dillution : WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Research Area: Signal Transduction