Anti- VTA1 Antibody | FNab09460

Anti- VTA1 Antibody | FNab09460 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR (By similarity) . Involved in HIV-1 budding.

Immunogen: Vps20-associated 1 homolog (S. cerevisiae)

synonyms: C6orf55, DRG 1, DRG1, FLJ27228, HSPC228, LIP5, LYST interacting protein 5, My012, SBP1, SKD1 binding protein 1, VTA1

Molecular weight (observed) : 45 kDa

Reactivity Species: Human, Mouse, Rat

Tested Application: ELISA, WB

Recomended Dillution : WB: 1:1000-1:10000;IF: 1:10-1:100

Research Area: Signal Transduction