Anti- WISP1 Antibody | FNab09514

Anti- WISP1 Antibody | FNab09514 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Downstream regulator in the Wnt/Frizzled-signaling pathway. Associated with cell survival. Attenuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase. Up-regulates the anti-apoptotic Bcl-X (L) protein. Adheres to skin and melanoma fibroblasts. In vitro binding to skin fibroblasts occurs through the proteoglycans, decorin and biglycan.

Immunogen: WNT1 inducible signaling pathway protein 1

synonyms: CCN family member 4, CCN4, WISP 1, WISP1, WISP1c, WISP1i, WISP1tc, Wnt 1 induced secreted protein

Molecular weight (observed) : 45 kDa

Reactivity Species: Human, Mouse

Tested Application: ELISA, WB, IHC

Recomended Dillution : WB: 1:200-1:2000; IHC: 1:20-1:200

Research Area: Immunology, Cancer, Stem Cells