Anti-XRCC1 monoclonal Antibody | MB62450

Anti-XRCC1 monoclonal Antibody | MB62450 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: IF, WB

Application Range: WB 1:2000, IF 1:100

Background: The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: X-ray repair complementing defective repair in Chinese hamster cells 1

Molecular Weight: 69.3 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: RCC

Immunogen: Full length human recombinant protein of human XRCC1 (NP_006288) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A