Anti- ZGPAT Antibody | FNab09634

Anti- ZGPAT Antibody | FNab09634 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. Isoform 4: Antagonizes the transcription repression by isoform 1 by competing for the binding of the NuRD complex. Does not bind DNA.

Immunogen: zinc finger, CCCH-type with G patch domain

synonyms: ZGPAT, ZC3HDC9, ZC3H9, KIAA1847, GPATCH6

Molecular weight (observed) : 57 kDa

Reactivity Species: Human, Mouse

Tested Application: ELISA, IHC, WB

Recomended Dillution : WB: 1:500-1:5000

Research Area: Metabolism