710
Anti- ZIP8 Antibody | FNab09643
- SKU:
- 710-FNab09643-GEN
- Availability:
- In Stock - Delivery within a week
Description
Anti- ZIP8 Antibody | FNab09643 | Gentaur UK, US & Europe Distribution
Form: liquid
Purification: Immunogen affinity purified
Purity: ≥95% as determined by SDS-PAGE
Host: Rabbit
Clonality: polyclonal
Clone ID: N/A
Isotype: IgG
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: SLC39A8 also known as ZIP8 belongs to the ZIP family of metal ion transporters which function to transport zinc and/or other metal ion substrates from the extracellular space or organellar lumen into the cytoplasm. Recently it was found that Zip8 expression is upregulated in human monocytes in response to LPS, TNF-α, and live bacteria, facilitating cytoprotection during the early inflammation. Besides zinc ZIP8 can also transport cadmium and manganese efficiently. It is predicted that ZIP8 contains 3 potential N-linked glycosylation sites and is subject to glycosylation, which may account for the presences of multiple molecular weights, such as 43 kDa, 49 kDa, 60 kDa, 75-90 kDa, 150 kDa, and 200 kDa.
Immunogen: solute carrier family 39 (zinc transporter), member 8
synonyms: BIGM103, PP3105, SLC39A8, ZIP 8, ZIP8
Molecular weight (observed) : 53 kDa, 75-90 kDa
Reactivity Species: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IP
Recomended Dillution : WB: 1:500-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:10-1:100
Research Area: Signal Transduction, Metabolism