AP3S1 Antibody (N-term) [APR14977G]

AP3S1 Antibody (N-term) [APR14977G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This AP3S1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human AP3S1.

Cellular Localisation: Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex

Molecular Weight: 21732

Clone: Polyclonal

Gene Name: AP3S1

Gene ID: 1176

Function: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

Summary: Tissue Location: Present in all adult tissues examined.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P

Dilution: WB--1:1000 IHC-P--1:100~500

Synonyms: AP-3 complex subunit sigma-1, AP-3 complex subunit sigma-3A, Adaptor-related protein complex 3 subunit sigma-1, Clathrin-associated/assembly/adaptor protein, small 3, Sigma-3A-adaptin, Sigma3A-adaptin, Sigma-adaptin 3a, AP3S1, CLAPS3