APBA2 Polyclonal Antibody | E-AB-12975

APBA2 Polyclonal Antibody | E-AB-12975 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Adapter protein X11beta, Amyloid beta A4 precursor protein-binding family A member 2, APBA2, APBA2, D15S1518E, HsT16821, LIN 10, MGC:14091, MGC99508, Mint 2, Mint-2, MINT2, Neuron-specific X11L protein, Neuronal Munc18-1-interacting protein 2, Phosphotyrosine binding/interacting domain (PTB) bearing protein, X11 beta, X11 like protein, X11l

Application: IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Neuroscience

Background: The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene.

Concentration: 0.6 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human APBA2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:100-1:300

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A