APC Anti-Human CD107a/LAMP-1 Antibody[H4A3] | E-AB-F1149E

APC Anti-Human CD107a/LAMP-1 Antibody[H4A3] | E-AB-F1149E | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: Lysosome-Associated Membrane Protein 1, LGP-120, LAMP-1

Swissprot Code: P11279

Application: FCM

Reactivity: Human

Host: Mouse

Isotype: Mouse IgG1, κ

Research Areas: Cancer, Metabolism, Neuroscience, Signal transduction, Stem cells, Tags & Cell Markers

Backgroun: CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.

Concentration: N/A

Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Immunogen: N/A

Buffer: PBS with 0.05% Proclin300, 1% BSA

Purification Method: N/A

Dilution: N/A

Clone: H4A3

Conjugation: APC

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A