APC Anti-Human CD273/PD-L2 Antibody[24F.10C12] | E-AB-F1175E

APC Anti-Human CD273/PD-L2 Antibody[24F.10C12] | E-AB-F1175E | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: B7DC, CD273, PDCD1L2, PDL2

Swissprot Code: Q9BQ51

Application: FCM

Reactivity: Mouse

Host: Rat

Isotype: Rat IgG2a, λ

Research Areas: Immunology

Backgroun: CD273, known as B7-DC, is also called programmed death ligand 2 (PDL2). This ligand is a 25 kD type I transmembrane protein and a member of B7 family within the immunoglobulin receptor superfamily and is expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. CD273 has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. CD273 has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions.

Concentration: N/A

Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Immunogen: N/A

Buffer: PBS with 0.05% Proclin300, 1% BSA

Purification Method: N/A

Dilution: N/A

Clone: 24F.10C12

Conjugation: APC

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A