APC Anti-Human CD61 Antibody[VI-PL2] | E-AB-F1166E

APC Anti-Human CD61 Antibody[VI-PL2] | E-AB-F1166E | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: GP3A,GPIIIa,ITGB3,Integrin beta-3

Swissprot Code: P05106

Application: FCM

Reactivity: Human

Host: Mouse

Isotype: Mouse IgG1, κ

Research Areas: Cancer, Cardiovascular, Signal transduction

Backgroun: CD61, also known as integrin β3 and glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of the integrin family, associating with platelet gpIIb (CD41) to form CD41/CD61 complex and with integrin αV (CD51) to form αV/β3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF, and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, macrophages, and some tumor cells involved in tumor metastasis, and in adenovirus infection through binding to RGD motif in extracellular matrix proteins.

Concentration: N/A

Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Immunogen: N/A

Buffer: PBS with 0.05% Proclin300, 1% BSA

Purification Method: N/A

Dilution: N/A

Clone: VI-PL2

Conjugation: APC

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A