APC Anti-Mouse CD119 Antibody[GR-20] | E-AB-F1115UE

APC Anti-Mouse CD119 Antibody[GR-20] | E-AB-F1115UE | Gentaur UK, US & Europe Distribution

Category: Flowcytometry Antibody

Synonyms: Interferon gamma receptor 1,Ifngr1,IFN-gamma-R1,IFN-gamma-R-alpha,CD119

Swissprot Code: P15261

Application: FCM

Reactivity: Human

Host: Mouse

Isotype: Mouse IgG1, κ

Research Areas: Immunology,Microbiology,Stem Cells,Kits/ Lysates/ Other

Backgroun: CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.

Concentration: 0.2 mg/mL

Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Immunogen: N/A

Buffer: PBS with 0.05% Proclin300, 1% BSA

Purification Method: N/A

Dilution: N/A

Clone: GR-20

Conjugation: APC

Moleculair Weight(Calculated): N/A

Moleculair Weight(Observed): N/A