Description
APC Anti-Mouse CD183/CXCR3 Antibody[CXCR3-173] | E-AB-F1114E | Gentaur UK, US & Europe Distribution
Category: Flowcytometry Antibody
Synonyms: C-X-C chemokine receptor type 3,Cxcr3,CXC-R3,CXCR-3,Interferon-inducible protein 10 receptor,IP-10 receptor,CD183
Swissprot Code: O88410
Application: FCM
Reactivity: Mouse
Host: Rat
Isotype: Rat IgM, κ
Research Areas: Cancer, Cardiovascular, Immunology, Signal transduction
Backgroun: CD183, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.
Concentration: N/A
Storage: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
Immunogen: N/A
Buffer: PBS with 0.05% Proclin300, 1% BSA
Purification Method: N/A
Dilution: N/A
Clone: CXCR3-173
Conjugation: APC
Moleculair Weight(Calculated): N/A
Moleculair Weight(Observed): N/A