APC2 Antibody (N-Term) [APR33369G]

APC2 Antibody (N-Term) [APR33369G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This APC2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 122-152 amino acids from human APC2.

Cellular Localisation: Cytoplasm, cytoskeleton. Golgi apparatus. Cytoplasm Cytoplasm, perinuclear region Note=Associated with actin filaments (PubMed:11691822, PubMed:25753423) . Associated with microtubule network (PubMed:10644998, PubMed:11691822, PubMed:25753423) .

Molecular Weight: 243949

Clone: Polyclonal

Gene Name: APC2 (HGNC:24036)

Gene ID: 10297

Function: Stabilizes microtubules and may regulate actin fiber dynamics through the activation of Rho family GTPases (PubMed:25753423) . May also function in Wnt signaling by promoting the rapid degradation of CTNNB1 (PubMed:10021369, PubMed:11691822, PubMed:9823329) .

Summary: Tissue Location: Widely expressed (at protein level) . Specifically expressed in the CNS.

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Adenomatous polyposis coli protein 2, Adenomatous polyposis coli protein-like, APC-like, APC2, APCL