APLP1 Antibody (C-Term) [APR33625G]

APLP1 Antibody (C-Term) [APR33625G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This APLP1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 505-539 amino acids from the human region of human APLP1.

Cellular Localisation: Cell membrane; Single-pass type I membrane protein

Molecular Weight: 72176

Clone: Polyclonal

Gene Name: APLP1

Gene ID: 333

Function: May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity) . Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I.

Summary: Tissue Location: Expressed in the cerebral cortex where it is localized to the postsynaptic density (PSD)

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB, FC

Dilution: FC--1:25 WB--1:2000

Synonyms: Amyloid-like protein 1, APLP, APLP-1, C30, APLP1