APLP2 Antibody (C-term) [APR11440G]

APLP2 Antibody (C-term) [APR11440G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This APLP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 593-621 amino acids from the C-terminal region of human APLP2.

Cellular Localisation: Cell membrane; Single-pass type I membrane protein. Nucleus

Molecular Weight: 86956

Clone: Polyclonal

Gene Name: APLP2 (HGNC:598)

Gene ID: 334

Function: May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3' (CDEI box) . Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity) .

Summary: Tissue Location: Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P

Dilution: WB--1:1000 IHC-P--1:100~500

Synonyms: Amyloid-like protein 2, APLP-2, APPH, Amyloid protein homolog, CDEI box-binding protein, CDEBP, APLP2, APPL2