ApoA1 Antibody | 5695

ApoA1 is a 29.0 kDa protein produced in the liver and intestine, and secreted as the predominant constituent of nascent high-density lipoprotein (HDL) particle. ApoA1 which is found exclusively in HDL has a unique ability to capture and solubilize free cholesterol. This ApoA-I ability enables HDL to remove excess peripheral cholesterol and return it to the liver for recycling and excretion. This process, called reverse cholesterol transport, is tho?ght to inhibit atherogenesis. For this reason HDL is also known as the “good cholesterol.” The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of ApoA-I (called ApoA1 Milano). Rat ApoA1 s a 27.4 kDa protein of 235 amino acid residues.

5695 | ApoA1 Antibody DataSheet

Antibody Target: ApoA1

Target Alternative Name: Apolipoprotein A-1, Apo-A1, ApoA-1,

Tag Line:

Category: ApoA

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Rat

Immunogen Sequence: E. coli expressed recombinant rat ApoA1

Accession #: P04639

Gene ID: 25081

Appearance: Colorless liquid

Form: Liquid

Concentration: 0.5 mg/ml

Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit anti-rat A1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% thimerosal.

Purification: Affinity purified

Application: Western blot

Positive Control:

Application And Usages: Western blot analysis (0.5-4 µg/ml). Recombinant rat ApoA1 (Cat.#: 4695-100) can be use as a positive control. However, the optimal conditions should be determined individually. Other applications have not been determined.

Country of Animal Origin: China

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: Verified

Immunocytochemistry Verified: Not Verified

Immunofluorescence Verified: Not Verified

Immunoprecipitation Verified: Not Verified

FACS Verified:

ELISA Verified: Not Verified

ChIP Verified: Not Verified

Dot Blot Verified:

Flow Cytometry Verified: Not Verified