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Apolipoprotein CIII Antibody Human | Gentaur

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SKU:: 552-33A-G2a-GEN-GEN
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Description
Additional Information

Description

Apolipoprotein CIII Antibody Human

Species Reactivity Human, Rat

Host/Isotype Rabbit / IgG

Class Recombinant Polyclonal

Type Antibody

Clone 6HCLC

Immunogen Peptide corresponding to amino acids 37–48 of human Apolipoprotein C3

Conjugate Unconjugated

Form Liquid

Concentration 0.5 mg/mL

Purification Protein A

Storage buffer PBS

Contains 0.09% sodium azide

Storage conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

RRID AB_2532651

Product Specific Information

This antibody is predicted to react with mouse, non-human primate, rabbit and porcine based on sequence homology.

Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody.

While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.

Target Information

Apolipoprotein C-III, also known as apo-CIII, is a protein that in humans is encoded by the APOC3 gene. Apo-CIII is a component of very low density lipoprotein (VLDL). APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles.

The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.

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