APPL1 monoclonal Antibody | MB62476

APPL1 monoclonal Antibody | MB62476 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: WB

Application Range: WB 1:500

Background: The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1

Molecular Weight: 79.5 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: APPL; DIP13alpha; MODY14

Immunogen: Full length human recombinant protein of human APPL1 (NP_036228) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A