AQPEP Antibody (C-Term) [APR33200G]

AQPEP Antibody (C-Term) [APR33200G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This AQPEP antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 844-877 amino acids from human AQPEP.

Cellular Localisation: Membrane; Single- pass type II membrane protein

Molecular Weight: 113283

Clone: Polyclonal

Gene Name: LVRN (HGNC:26904)

Gene ID: 206338

Function: Metalloprotease which may be important for placentation by regulating biological activity of key peptides at the embryo-maternal interface. On synthetic substrates it shows a marked preference for Leu-4-methylcoumaryl-7-amide (Leu-MCA) over Met-MCA, Arg-LCA and Lys- LCA. Cleaves the N-terminal amino acid of several peptides such as angiotensin-3, kisspeptin-10 and endokinin C.

Summary: Tissue Location: Specifically expressed in placenta and not in other tissues. Mainly found at the cell surface region of the extravillous trophoblasts. Detected on extravillous trophoblasts in the outer layer of the chorion laeve in the fetal membrane Not detected on either fetal amnionic epithelial cells or maternal decidual cells. Also detected in the migrating extravillous trophoblasts in the maternal decidual tissues (at protein level) .

Form: N/A

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:2000

Synonyms: Aminopeptidase Q, AP-Q, 3411-, CHL2 antigen, Laeverin, AQPEP, LVRN