AREG polyclonal Antibody | BS7305

AREG polyclonal Antibody | BS7305 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB,IHC,IF

Application Range: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Background: Amphiregulin (AREG) is one of the ligands of the epidermal growth factor receptor (EGFR) . AREG plays a central role in mammary gland development and branching morphogenesis in organs and is expressed both in physiological and in cancerous tissues. The AREG protein is synthesized as a 252-amino acid transmembrane precursor, pro-AREG. At the plasma membrane, pro-AREG is subjected to sequential proteolytic cleavages within its ectodomain and is then released as the soluble AREG protein. Depending on the cell type and microenvironment, AREG can be produced in multiple cellular and mature forms using alternative pro-AREG cleavage sites and glycosylation motifs.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: AREG polyclonal Antibody detects endogenous levels of AREG protein.

Molecular Weight: ~44 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: A REG; Amphiregulin; AR; AR; AREG; AREG_HUMAN; AREGB; Colorectum cell derived growth factor; Colorectum cell derived growth factor; Colorectum cell-derived growth factor; CRDGF; CRDGF; MGC13647; Schwannoma derived growth factor; SDGF;

Immunogen: Recombinant full length Human AREG.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: