Description
ARF1 polyclonal Antibody | BS90083 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Application: WB IHC FC
Application Range: WB:1:1,000-1:2,000 IHC:1:50-1:200 FC:1:50-1:100
Background: ADP-ribosylation factors (ARFs), are small guanine nucleotide-binding proteins that enhance the enzymatic activities of cholera toxin, and constitute one family of the RAS superfamily. ARFs are essential and ubiquitous in eukaryotes, as they are involved in vesicular transport and functioning via phospholipase D activation. ARF proteins play a role in membrane traffic and organelle integrity and are intimately tied to their reversible association with membranes and distinct interactions with membrane phospholipids. ARF1 is regulated by the binding and hydrolysis of GTP. Coatomer, or COPI, is a heptameric protein recruited to membranes by ARF1. Research demonstrates that guanine nucleotide exchange-activated ARF1, when located at the Golgi membrane, recruits and binds cytoplasmic COPI to the membranes.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: ARF1 polyclonal Antibody detects endogenous levels of ARF1 protein.
Molecular Weight: 21 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: ARF1, ADP Ribosylation Factor 1, ADP-ribosylation factor 1, ARF 1, ARF1, ARF1,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: ProA affinity purified
Pathway: