Argatroban | 9670

Agatroban is a potent and competitive thrombin inhibitor (Ki = 19 nM) that displays anticoagulant activity. Active in vivo.

Agatroban is a potent and competitive thrombin inhibitor (Ki = 19 nM) that displays anticoagulant activity. Active in vivo.

9670 | Argatroban DataSheet

Alternate Name/Synonyms: (2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(3R)-3-methyl-1,2,3,4-tetrahydroquinolin-8-yl]sulfonylamino]pentanoyl]-4-methyl-piperidine-2-carboxylic acid

Appearance: Off-white solid

Formulation: N/A

CAS Number: 141396-28-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₃H₃₆N₆O₅S

Molecular Weight: 508.64

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>30 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent, competitive thrombin inhibitor

MDL Number: N/A

PubChem CID: 92722

SMILES: CC1CCN(C(C1)C(=O)O)C(=O)C(CCCN=C(N)N)NS(=O)(=O)C2=CC=CC3=C2NCC(C3)C

InChi: InChI=1S/C23H36N6O5S/c1-14-8-10-29(18(12-14)22(31)32)21(30)17(6-4-9-26-23(24)25)28-35(33,34)19-7-3-5-16-11-15(2)13-27-20(16)19/h3,5,7,14-15,17-18,27-28H,4,6,8-13H2,1-2H3,(H,31,32)(H4,24,25,26)/t14-,15?,17+,18-/m1/s1

InChi Key: KXNPVXPOPUZYGB-IOVMHBDKSA-N